The VitalWhys Journal
Articles
Long-form pieces on longevity, training, sleep, and living deliberately. No fluff. Written for people who treat health like it matters.
longevity
Berberine vs. Metformin for Anti-Aging: What the Longevity Research Actually Says
Both berberine and metformin activate AMPK — a cellular pathway strongly implicated in aging. But the longevity evidence behind each is very different. Here's what the research shows and what it doesn't.
May 30, 2026 · 8 min read
supplementation
Berberine vs. Metformin for Weight Loss: What the Research Actually Shows
Both berberine and metformin produce modest weight loss in clinical trials. But the mechanisms differ, the populations differ, and one requires a prescription. Here's what the evidence actually says.
May 30, 2026 · 8 min read
supplementation
Berberine vs. Metformin: What the Research Actually Says About Both
Berberine has been called 'nature's metformin.' The comparison isn't quite accurate, but the mechanisms overlap in interesting ways. Here's what the research shows on both — and which is appropriate for what situation.
April 30, 2026 · 8 min read